4iyr | pdb_00004iyr

Crystal structure of full-length caspase-6 zymogen

spinqualitylabelsall models 4iyr, resolution 2.70Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4iyr is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 3nr2, 3v6l, 3v6m, 3od5 Gene: CASP6 (HUMAN) Activity: Caspase-6, with EC number 3.4.22.59 Resources: FirstGlance, OCA, RCSB, PDBsum Function [CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. See Also Caspase

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