3k6l | pdb_00003k6l

The structure of E.coli peptide deformylase (PDF) in complex with peptidomimetic ligand BB2827

spinqualitylabelsall models 3k6l, resolution 2.15Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3k6l is a 3 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 2BB, NI Gene: def, fms, b3287, JW3248 (Escherichia coli K-12) Activity: Peptide deformylase, with EC number 3.5.1.88 Resources: FirstGlance, OCA, RCSB, PDBsum Function [DEF_ECOLI] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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