4l5f | pdb_00004l5f

Crystal Structure of DENV1-E106 Fab bound to DENV-1 Envelope protein DIII

spinqualitylabelsall models 4l5f, resolution 2.45Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4l5f is a 3 chain structure with sequence from Dengue virus 1 and Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: E (Dengue virus 1) Resources: FirstGlance, OCA, RCSB, PDBsum Function [Q8BE40_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774] See Also Monoclonal Antibody

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