4v06 | pdb_00004v06

Crystal structure of human tryptophan hydroxylase 2 (TPH2), catalytic domain

spinqualitylabelsall models 4v06, resolution 2.63Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4v06 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: FE, IMD Activity: Tryptophan 5-monooxygenase, with EC number 1.14.16.4 Resources: FirstGlance, OCA, RCSB, PDBsum Disease [TPH2_HUMAN] Disease susceptibility is associated with variations affecting the gene represented in this entry. Disease susceptibility is associated with variations affecting the gene represented in this entry. Naturally occurring variants of TPH2 with impaired enzyme activity could cause deficiency of serotonin production and result in an increased risk of developing behavioral disorders.

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