3mdx | pdb_00003mdx

Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, rhombohedral crystal form

spinqualitylabelsall models 3mdx, resolution 1.45Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3mdx is a 1 chain structure with sequence from Brucella melitensis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: EDO Related: 3mbq Gene: dut, BAB1_1687 (Brucella melitensis) Activity: dUTP diphosphatase, with EC number 3.6.1.23 Resources: FirstGlance, OCA, RCSB, PDBsum Function [DUT_BRUA2] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[HAMAP-Rule:MF_00116] Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also Deoxyuridine 5'-triphosphate nucleotidohydrolase

Proteopedia Page Contributors and Editors (what is this?)

OCA