4fo4 | pdb_00004fo4

Inosine 5'-monophosphate dehydrogenase from Vibrio cholerae, deletion mutant, complexed with IMP and mycophenolic acid

spinqualitylabelsall models 4fo4, resolution 2.03Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4fo4 is a 2 chain structure with sequence from Vibrio cholerae o1 biovar el tor. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: IMP, K, MOA Related: 4fez, 4ff0 Gene: VC0767, VC_0767 (Vibrio cholerae O1 biovar El Tor) Activity: IMP dehydrogenase, with EC number 1.1.1.205 Resources: FirstGlance, OCA, RCSB, PDBsum Function [Q9KTW3_VIBCH] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964] See Also Inosine monophosphate dehydrogenase

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