1p9k | pdb_00001p9k

THE SOLUTION STRUCTURE OF YBCJ FROM E. COLI REVEALS A RECENTLY DISCOVERED ALFAL MOTIF INVOLVED IN RNA-BINDING

spinqualitylabelsall models 1p9k, 20 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1p9k is a 1 chain structure with sequence from Escherichia coli k-12. This structure supersedes the now removed PDB entry 1o09. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: ybcJ (Escherichia coli K-12) Resources: FirstGlance, OCA, RCSB, PDBsum, TOPSAN Function [YBCJ_ECOLI] Its structure and the presence of conserved basic residues indicates that it probably binds RNA. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMed The structure of the recombinant Escherichia coli protein YbcJ, a representative of a conserved family of bacterial proteins (COG2501), was determined by nuclear magnetic resonance. The fold of YbcJ identified it as a member of the larger family of S4-like RNA binding domains. These domains bind to structured RNA, such as that found in tRNA, rRNA, and a pseudoknot of mRNA. The structure of YbcJ revealed a highly conserved patch of basic residues, comprising amino acids K26, K38, R55, K56, and K59, which likely participate in RNA binding. The solution structure of YbcJ from Escherichia coli reveals a recently discovered alphaL motif involved in RNA binding.,Volpon L, Lievre C, Osborne MJ, Gandhi S, Iannuzzi P, Larocque R, Cygler M, Gehring K, Ekiel I J Bacteriol. 2003 Jul;185(14):4204-10. PMID:12837795 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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