1ug7 | pdb_00001ug7
From Proteopedia
Solution structure of four helical up-and-down bundle domain of the hypothetical protein 2610208M17Rik similar to the protein FLJ12806
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Structural highlights
Function[AIDA_MOUSE] Acts as a ventralizing factor during embryogenesis (By similarity). Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling. Contents | ||||||||||||||||||
This page was last modified 15:47, 25 December 2014.