4giy | pdb_00004giy

tRNA Guanine Transglycosylase in complex with disubstituted lin-benzoguanine inhibitor

spinqualitylabelsall models 4giy, resolution 1.75Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4giy is a 1 chain structure with sequence from Zymomonas mobilis subsp. mobilis zm4 = atcc 31821. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 0WY, ZN Related: 3eos, 4gi1, 4gh3 Gene: tgt, ZMO0363 (Zymomonas mobilis subsp. mobilis ZM4 = ATCC 31821) Activity: tRNA-guanine(34) transglycosylase, with EC number 2.4.2.29 Resources: FirstGlance, OCA, RCSB, PDBsum Function [TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168] See Also TRNA-guanine transglycosylase

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