4fgk | pdb_00004fgk

Oxidized quinone reductase 2 in complex with chloroquine

spinqualitylabelsall models 4fgk, resolution 1.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4fgk is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 0TX, FAD, ZN Related: 4fgj Gene: NMOR2, NQO2 (Homo sapiens) Activity: Ribosyldihydronicotinamide dehydrogenase (quinone), with EC number 1.10.99.2 Resources: FirstGlance, OCA, RCSB, PDBsum Function [NQO2_HUMAN] The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. See Also Quinone reductase

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