4fgt | pdb_00004fgt

Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme.

spinqualitylabelsall models 4fgt, resolution 2.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4fgt is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: SO4 NonStd Res: CME Related: 3n5e, 3egy Gene: TYMS, TS, OK/SW-cl.29 (Homo sapiens) Activity: Thymidylate synthase, with EC number 2.1.1.45 Resources: FirstGlance, OCA, RCSB, PDBsum Function [TYSY_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. See Also Thymidylate synthase

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