3wo4 | pdb_00003wo4

Crystal structure of the IL-18 signaling ternary complex

spinqualitylabelsall models 3wo4, resolution 3.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3wo4 is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: BMA, CL, NAG, FUC, MAN Related: 3wo2, 3wo3 Resources: FirstGlance, OCA, RCSB, PDBsum Function [IL18_HUMAN] Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. [IL18R_HUMAN] Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B.

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