3p45 | pdb_00003p45

Crystal structure of apo-caspase-6 at physiological pH

spinqualitylabelsall models 3p45, resolution 2.53Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3p45 is a 16 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: CASP6 (Homo sapiens) Resources: FirstGlance, OCA, RCSB, PDBsum Function [CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. See Also Caspase

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