2f8i | pdb_00002f8i
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| 2f8i, resolution 1.541Å | |||||||||||||
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| Ligands: | 205 | ||||||||||||
| Gene: | TTR, PALB (Homo sapiens) | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Human transthyretin (TTR) complexed with Benzoxazole
Disease
Known diseases associated with this structure: Amyloid neuropathy, familial, several allelic types OMIM:[176300], Amyloidosis, senile systemic OMIM:[176300], Carpal tunnel syndrome, familial OMIM:[176300], Dystransthyretinemic hyperthyroxinemia OMIM:[176300]
About this Structure
2F8I is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action., Razavi H, Palaninathan SK, Powers ET, Wiseman RL, Purkey HE, Mohamedmohaideen NN, Deechongkit S, Chiang KP, Dendle MT, Sacchettini JC, Kelly JW, Angew Chem Int Ed Engl. 2003 Jun 23;42(24):2758-61. PMID:12820260
Page seeded by OCA on Thu Mar 20 16:49:22 2008
