4kvr | pdb_00004kvr

Crystal Structure of Prochlorococcus marinus aldehyde-deformylating oxygenase (mutant V41Y)

spinqualitylabelsall models 4kvr, resolution 1.88Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4kvr is a 1 chain structure with sequence from Prochlorococcus marinus str. mit 9313. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 6NA, FE Related: 2oc5, 4kvq, 4kvs Gene: PMT_1231 (Prochlorococcus marinus str. MIT 9313) Activity: Octadecanal decarbonylase, with EC number 4.1.99.5 Resources: FirstGlance, OCA, RCSB, PDBsum Function [ALDEC_PROMM] Catalyzes the decarbonylation of fatty aldehydes to alkanes. Requires the presence of ferredoxin, ferredoxin reductase and NADPH for in vitro decarbonylase activity (By similarity). Involved in the biosynthesis of alkanes, mainly heptadecane and pentadecane. Publication Abstract from PubMed Biocatalytic propane production: structure-based engineering of aldehyde-deformylating oxygenase improves specificity for short- and medium-chain-length aldehydes and enhances the propane generation in whole-cell biotransformations. This presents new opportunities for developing biocatalytic modules for the production of volatile "drop-in" biofuels. Production of Propane and Other Short-Chain Alkanes by Structure-Based Engineering of Ligand Specificity in Aldehyde-Deformylating Oxygenase.,Khara B, Menon N, Levy C, Mansell D, Das D, Marsh EN, Leys D, Scrutton NS Chembiochem. 2013 Jun 11. doi: 10.1002/cbic.201300307. PMID:23757044 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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