4gom | pdb_00004gom

Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Aza-SAM

spinqualitylabelsall models 4gom, resolution 2.45Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4gom is a 3 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 0Y0 Related: 4gbe, 4gol, 4gon, 4goo Gene: b3387, dam, JW3350 (ECOLI) Activity: Site-specific DNA-methyltransferase (adenine-specific), with EC number 2.1.1.72 Resources: FirstGlance, OCA, RCSB, PDBsum Function [DMA_ECOLI] Methylates DNA within the sequence GATC and protects the DNA from cleavage by the restriction endonuclease MboI. Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in postreplication mismatch repair rather than as a part of a restriction modification system. May also play a role in DNA replication.

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