2mm4 | pdb_00002mm4

Structure of a Conserved Golgi Complex-targeting Signal in Coronavirus Envelope Proteins

spinqualitylabelsall models 2mm4, 15 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2mm4 is a 1 chain structure with sequence from Cvhsa. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Gene: E (CVHSA) Resources: FirstGlance, OCA, RCSB, PDBsum Function [VEMP_CVHSA] Component of the viral envelope that plays a central role in virus morphogenesis and assembly. It is sufficient to form virus-like particles. Seems to be important for creating the membrane curvature needed to acquire the rounded, stable and infectious particle phenotype. Acts as a viroporin, inducing the formation of hydrophilic pores in cellular membranes. Also induces apoptosis (By similarity).

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