3pp2 | pdb_00003pp2

Crystal structure of the pleckstrin homology domain of ArhGAP27

spinqualitylabelsall models 3pp2, resolution 1.42Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3pp2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CIT, GOL, UNX Gene: ARHGAP27, CAMGAP1, SH3D20, PP905 (Homo sapiens) Resources: FirstGlance, OCA, RCSB, PDBsum Function [RHG27_HUMAN] Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).

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