4f45 | pdb_00004f45

Crystal structure of human CD38 E226Q mutant in complex with NAADP

spinqualitylabelsall models 4f45, resolution 2.10Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4f45 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: DN4 Related: 4f46 Gene: CD38 (Homo sapiens) Activity: NAD(+) nucleosidase, with EC number 3.2.2.5 Resources: FirstGlance, OCA, RCSB, PDBsum Function [CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. See Also Cluster of Differentiation CD38

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