2j6c | pdb_00002j6c
CRYSTAL STRUCTURE OF AFV3-109, A HIGHLY CONSERVED PROTEIN FROM CRENARCHAEAL VIRUSES
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Overview
The extraordinary morphologies of viruses infecting hyperthermophilic, archaea clearly distinguish them from bacterial and eukaryotic viruses., Moreover, their genomes code for proteins that to a large extend have no, related sequences in the extent databases. However, a small pool of genes, is shared by overlapping subsets of these viruses, and the most conserved, gene, exemplified by the ORF109 of the Acidianus Filamentous Virus 3, AFV3, is present on genomes of members of three viral familes, the, Lipothrixviridae, Rudiviridae, and "Bicaudaviridae", as well as of the, unclassified Sulfolobus Turreted Icosahedral Virus, STIV. We present here, the crystal structure of the protein (Mr = 13.1 kD, 109 residues) encoded, by the AFV3 ORF 109 in two different crystal forms at 1.5 and 1.3 A, ... [(full description)]
About this Structure
2J6C is a [Single protein] structure of sequence from [Acidianus filamentous virus 1] with GOL as [ligand]. Full crystallographic information is available from [OCA].
Reference
Crystal structure of AFV3-109, a highly conserved protein from crenarchaeal viruses., Keller J, Leulliot N, Cambillau C, Campanacci V, Porciero S, Prangishvilli D, Forterre P, Cortez D, Quevillon-Cheruel S, van Tilbeurgh H, Virol J. 2007 Jan 22;4:12. PMID:17241456
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