4irq | pdb_00004irq

Crystal structure of catalytic domain of human beta1,4galactosyltransferase 7 in closed conformation in complex with manganese and UDP

spinqualitylabelsall models 4irq, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4irq is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: MN, TRS, UDP Related: 4irp, 3lw6 Gene: 4galactosyltransferase, B4GALT7, beta1, UNQ748/PRO1478, XGALT1 (Homo sapiens) Resources: FirstGlance, OCA, RCSB, PDBsum Disease [B4GT7_HUMAN] Ehlers-Danlos syndrome, progeroid type. The disease is caused by mutations affecting the gene represented in this entry. Function [B4GT7_HUMAN] Required for the biosynthesis of the tetrasaccharide linkage region of proteoglycans, especially for small proteoglycans in skin fibroblasts.

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