4unp | pdb_00004unp

Mtb TMK in complex with compound 34

spinqualitylabelsall models 4unp, resolution 2.30Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4unp is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: TXW Related: 4unn, 4unq, 4unr, 4uns Activity: dTMP kinase, with EC number 2.7.4.9 Resources: FirstGlance, OCA, RCSB, PDBsum Function [KTHY_MYCTO] Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor. Situated at the junction of both de novo and salvage pathways of deoxythymidine triphosphate (dTTP) synthesis, is essential for DNA synthesis and cellular growth (By similarity).

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