4uu6 | pdb_00004uu6

CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF PALS1

spinqualitylabelsall models 4uu6, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4uu6 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: ACT, CL, GOL Related: 4uu5 Resources: FirstGlance, OCA, RCSB, PDBsum Function [MPP5_HUMAN] May play a role in tight junctions biogenesis and in the establishment of cell polarity in epithelial cells. May modulate SC6A1/GAT1-mediated GABA uptake by stabilizing the transporter. Required for localization of EZR to the apical membrane of parietal cells and may play a role in the dynamic remodeling of the apical cytoskeleton (By similarity).

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