3ag7 | pdb_00003ag7

An auxilin-like J-domain containing protein, JAC1 J-domain

spinqualitylabelsall models 3ag7, resolution 1.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3ag7 is a 1 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Related: 1nz6, 2qwo, 2qwr, 2qwp, 2qwq, 2qwn Gene: At1g75100, F9E10.5, JAC1 (Arabidopsis thaliana) Resources: FirstGlance, OCA, RCSB, PDBsum Publication Abstract from PubMed An auxilin-like J-domain-containing protein, JAC1, is necessary for chloroplast movement in Arabidopsis thaliana, to capture photosynthetic light efficiently under weak light conditions. Here, we performed crystallographic and functional analyses of the J-domain of JAC1. The crystal structure of the J-domain is quite similar to that of bovine auxilin, and possesses a similar positively charged surface, which probably forms the interface with the Hsp70 chaperone. The mutation of the highly conserved HPD motif of the JAC1 J-domain abrogated the chloroplast photorelocation response. These results suggest that the requirement of JAC1 in chloroplast photorelocation movement is attributable to the J-domain's cochaperone activity. Crystallographic and functional analyses of J-domain of JAC1 essential for chloroplast photorelocation movement in Arabidopsis thaliana.,Takano A, Suetsugu N, Wada M, Kohda D Plant Cell Physiol. 2010 Aug;51(8):1372-6. Epub 2010 Jun 20. PMID:20562448 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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