4x4w | pdb_00004x4w

Crystal structure of the full-length human mitochondrial CCA-adding enzyme

spinqualitylabelsall models 4x4w, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4x4w is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CL, FLC, GOL, SO4 Activity: CCA tRNA nucleotidyltransferase, with EC number 2.7.7.72 Resources: FirstGlance, OCA, RCSB, PDBsum Function [TRNT1_HUMAN] Isoform 1: Adds and repairs the conserved 3'-CCA sequence necessary for the attachment of amino acids to the 3' terminus of tRNA molecules, using CTP and ATP as substrates. Isoform 2: Adds 2 C residues (CC-) to the 3' terminus of tRNA molecules instead of a complete CCA end as isoform 1 does (in vitro).

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