5ajp | pdb_00005ajp

Crystal structure of the active form of GalNAc-T2 in complex with UDP and the glycopeptide MUC5AC-13

spinqualitylabelsall models 5ajp, resolution 1.65Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5ajp is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: A2G, MN, SO4, UDP Related: 5ajn, 5ajo Activity: Polypeptide N-acetylgalactosaminyltransferase, with EC number 2.4.1.41 Resources: FirstGlance, OCA, RCSB, PDBsum Function [GALT2_HUMAN] Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region.

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