Elastase

Elastase (ELA) is a chymotrypsin-like protease which breaks down proteins. The ELAs are numbered according to their genes. ELA2 (or PMN-ELA) is secreted by neutrophils during inflammation. For additional details see Serine Proteases.

3D structures of elastase

Updated on 29-March-2015

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• MMP12 See Matrix metalloproteinase
• MMP16 See Matrix metalloproteinase
• ELA1
  • 3mty, 3mu0, 3mu1, 3mu4, 3mu5, 3mu8, 3mnb, 3mnc, 3mns, 3mnx, 3mo3, 3mo6, 3mo9, 3moc, 3e3t, 2v0b, 2g4t, 2g4u, 2de8, 2blo, 2blq, 2a7c, 2a7j, 1gvk, 1qnj, 1lvy, 3est, 1est, 2oqu, 3odd, 3odf, 2bdc – pELA1 – pig
    
  • 3hgn – pELA1+peptidyl inhibitor – neutron
    
  • 3hgp, 2cv3, 2bdb, 2bcd, 2h1u, 1mmj, 1h9l, 1nes, 4est, 5est, 8est, 7est, 6est - pELA1+peptidyl inhibitor
    
  • 1fzz – pELA1+ONO-6818
    
  • 1qr3, 1qgf, 1bru, 1hv7, 1btu – pELA1+cyclic inhibitor
    
  • 1okx – pELA1 + scyptolin
    
  • 1e34, 1e35, 1e36, 1e37, 1e38 – pELA1-gamma-lactam
    
  • 1eai – pELA1+Ascaris inhibitor
    
  • 2d26 – pELA1+α-1-antitrypsin
    
  • 1fle – pELA1+elafin
    
  • 1b0e, 1b0f – pELA1+MDL
    
  • 2v35 – pELA1+JM54
    
  • 2iot – pELA1+clavulanic acid
    
  • 2de9 – pELA1+tris
    
  • 1uvo, 1uvp, 1lka, 1lkb – pELA1+ions
    
  • 1gwa – pELA1+I3
    
  • 1uo6, 1c1m – pELA1+Xe
    
  • 1l0z, 1l1g - pELA1+Xe+Br
    
  • 2bb4, 2bd2, 2bd3, 2bd4, 2bd5, 2bd7, 2bd8, 2bd9, 1hax, 1hay, 1haz, 1hb0, 1qix – pELA1+beta-casomorphin-7
    
  • 2bda – pELA1+N-acetyl-NPI
    
  • 1mcv – pELA1+squash inhibitor
    
  • 1bma – pELA1+aminimide
    
  • 1elf, 1elg – pELA1+peptidyl hydroxylamine
    
  • 1eld, 1ele, 1elb, 1ela, 1elc, 2est – pELA1+anilide inhibitor
    
  • 1esa, 1esb – pELA1 intermediate
    
  • 1eas, 1eat, 1eau – pELA1+pyridine inhibitor
    
  • 1inc – pELA1+benzoxazinone
    
  • 1jim, 9est, 8est – pELA1+coumarin derivative
    
  • 2fo9, 2foa, 2fob, 2foc, 2fod, 2foe, 2fof, 2fog, 2foh – pELA1+solvent
    
  • 4k89 – PaELA – Pseudomonas aeruginosa
    
  • 3dbk – PaELA+phophoramidon
    
  • 1u4g – PaELA+HPI
    
  • 1ezm - PaELA
    
  • 1elt – ELA - salmon
    
• ELA2
  • 3q76 – hELA2
    
  • 3q77 – hELA2+dihydropyrimidone inhibitor
    
  • 2z7f – hELA2 peptidase domain +antileukoproteinase
    
  • 2rg3 – hELA2+sulfonic inhibitor
    
  • 1h1b, 1ppg, 1hne – hELA2+inhibitor
    
  • 1ppf – hELA2+ovomucoid
    
  • 1b0f – hELA2+MDL101146
    
  • 4nzl – hELA2 + protein
    
  • 4wvp – hELA2 + activity-based probe
    

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