4rrx | pdb_00004rrx

Crystal Structure of Apo Murine V89W Cyclooxygenase-2 Complexed with Lumiracoxib

spinqualitylabelsall models 4rrx, resolution 2.78Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4rrx is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: BOG, LUR, NAG Related: 4rrw, 4rry, 4rrz, 4rs0 Activity: Prostaglandin-endoperoxide synthase, with EC number 1.14.99.1 Resources: FirstGlance, OCA, RCSB, PDBsum Function [PGH2_MOUSE] Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.

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