4ymd | pdb_00004ymd

CL-K1 trimer bound to man(alpha1-2)man

spinqualitylabelsall models 4ymd, resolution 2.87Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4ymd is a 6 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CA, GOL, MAN Resources: FirstGlance, OCA, RCSB, PDBsum Disease [COL11_HUMAN] Craniofacial-ulnar-renal syndrome. The disease is caused by mutations affecting the gene represented in this entry. Function [COL11_HUMAN] Lectin that binds to various sugars including fucose and mannose. Has a higher affinity for fucose compared to mannose. Does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. Also binds lipopolysaccharides (LPS). Involved in fundamental development serving as a guidance cue for neural crest cell migration (By similarity).

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