High mobility group protein

spinqualitylabelsall models Rat HMG1 tandem boxes complexed with DNA (PDB code 2gzk). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D High mobility group protein (HMG) is a chromatin protein which organizes the DNA and regulater transcription. HMG superfamilies differ by their DNA-binding domains. HMGAs bind via an AT-hook domain. HMGBs bind via box domain. HMGNs bind via a nucleosome binding domain. For details on HMGA see HMGI(Y).

3D Structures of high mobility group protein (HMG)

Updated on 21-April-2015

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• HMGA
  • HMGI(Y), 2eze, 2ezf, 2ezg – hHMG-1 + DNA - human
    
• HMGB
  • 1hme, 1hmf – rHMG-1 B domain – rat - NMR
    
  • 1aab – rHMG-1 A domain - NMR
    
  • 1ckt – rHMG-1 A domain + DNA
    
  • 2gzk – rHMG-1 tandem boxes + DNA
    
  • 2yrq – hHMG-1 tandem boxes - human - NMR
    
  • 2rtu – hHMG-1 box 1 - NMR
    
  • 2ly4 – hHMG-1 box domain + cellular tumor antigen p53 - NMR
    
  • 2eqz, 2yqi – hHMG-3 box domain - NMR
    
  • 1hsm, 1hsn, 1nhm, 1nhn – HMG-1 box domain – chinese hamster - NMR
    
  • 1hma – DmHMG-D DNA-binding domain – Drosophila melanogaster - NMR
    
  • 1qrv – DmHMG-D DNA-binding domain + DNA
    
  • 3nm9 – DmHMG-D DNA-binding domain (mutant) + DNA
    
  • 1e7j – DmHMG-D DNA-binding domain + DNA - NMR
    
  • 1j3d – pHMG-2 C terminal – pig - NMR
    
  • 1j3c – pHMG-2 C terminal (mutant) - NMR
    
  • 1j3x – pHMG-2 N terminal (mutant) - NMR
    
• HMG
  • 2mrc – HMG residues 17-99 – Plasmodium falciparum - NMR
    

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Michal Harel, Joel L. Sussman