2vp3 | pdb_00002vp3
From Proteopedia
DC26 MUTANT OF VACCINIA VIRUS PROTEIN VP39 IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND M7G(5')PPPG
| |||||||||||||
| 2vp3, resolution 1.95Å | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ligands: | SAH and M7G | ||||||||||||
| Activity: | Polynucleotide adenylyltransferase, with EC number 2.7.7.19 | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Overview
The specific binding of N7-methylguanine cap analogues to the RNA methyltransferase VP39 was observed through X-ray crystallography, providing a prototypical structure for a complex between a protein and an mRNA 5' cap.
About this Structure
2VP3 is a Single protein structure of sequence from Vaccinia virus. Full crystallographic information is available from OCA.
Reference
Specific protein recognition of an mRNA cap through its alkylated base., Hodel AE, Gershon PD, Shi X, Wang SM, Quiocho FA, Nat Struct Biol. 1997 May;4(5):350-4. PMID:9145102
Page seeded by OCA on Thu Mar 20 18:47:58 2008
