4ui0 | pdb_00004ui0

Crystal structure of the human RGMB-BMP2 complex, crystal form 2

spinqualitylabelsall models 4ui0, resolution 2.80Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4ui0 is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CL, FLC, MPD Related: 4uhy, 4uhz, 4ui1, 4ui2 Resources: FirstGlance, OCA, RCSB, PDBsum Function [BMP2_HUMAN] Induces cartilage and bone formation. [RGMB_HUMAN] Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.

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