4z34 | pdb_00004z34

Crystal Structure of Human Lysophosphatidic Acid Receptor 1 in complex with ONO9780307

spinqualitylabelsall models 4z34, resolution 3.00Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4z34 is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: 1WV, ON7 Related: 4z35, 4z36 Resources: FirstGlance, OCA, RCSB, PDBsum Function [LPAR1_HUMAN] Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.

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