Tryptase

Tryptase (TRP) is a serine protease found in mast cells. TRP is used as a marker for mast cell activation.

3D Structures of tryptase

Updated on 22-June-2015

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• Tryptase
  • 1lto – hTRP-α1 - human
    
  • 2f9o - hTRP-α1 (mutant)
• Tryptase complex with inhibitor
  • 1a0l – hTRP-β + APPA
    
  • 2f9n, 2f9p - hTRP-α1 (mutant) + leupeptin
    
  • 2bm2, 2fww - hTRP-β2 + piperidine derivative
    
  • 4a6l - hTRP-α/β1 + piperidine derivative
    
  • 4mpu, 4mpv, 4mpw, 4mpx, 4mqa - hTRP-α/β1 + drug
    
  • 2fxr - hTRP-β2 + ketone inhibitor
    
  • 2fpz - hTRP-β2 + benzimidazole inhibitor
    
  • 2fs9, 2fs8, 2gdd, 2za5, 2zeb, 2zec - hTRP-β2 + inhibitor
    
  • 3v7t - hTRP-β2 + tropanylamide inhibitor
    

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Michal Harel, Alexander Berchansky