Haptoglobin receptor

spinqualitylabelsall models IsdH NEAT-3 domain complex with hemoglobin subunitsα,β (PDB code 3szk) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Haptoglobin receptor (IsdH) is part of the iron-regulated surface determinant system that captures heme from the host hemoproteins. IsdH binds haptoglobin (Hp) which removes hemoglobin (Hb) from the blood by forming Hp-Hb complex. IsdH contains multiple NEAT (Near Transporter) domains which bind proteins and heme. For more details see Molecular Playground/Hemoglobin-Haptoglobin Complex.

3D Structures of haptoglobin receptor

Updated on 02-July-2015

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• IsdH NEAT-1 domain
  • Molecular Playground/Hemoglobin-Haptoglobin Complex – SaIsdH NEAT-1 domain – Staphylococcus aureus - NMR
    
  • 3ovu – SaIsdH NEAT-1 domain + Hb α + α-Hb-stabilizing protein
    
  • 4wjg – SaIsdH NEAT-1 domain + Hb α+β + Hp + Hp-Hb receptor
    
• IsdH NEAT-2 domain
  • 4fc3 – SaIsdH NEAT-2 domain + Hb α+β
    
• IsdH NEAT-3 domain
  • 3vua – SaIsdH NEAT-3 domain
    
  • 2z6f – SaIsdH NEAT-3 domain + heme
    
  • 3qug, 3quh, 3vtm – SaIsdH NEAT-3 domain + porphyrin
    
  • 3szk – SaIsdH NEAT-3 domain + Hb α+β
    
  • 3s48 – SaIsdH NEAT-3 domain + Hb α
    
• IsdH NEAT-2-3 domain
  • 4ij2, 4xs0 – SaIsdH NEAT-2-3 domain (mutant) + Hb α+β
    
• IsdH linker domain
  • 2lhr – SaIsdH linker domain - NMR
    

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