3jag | pdb_00003jag

Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon

spinqualitylabelsall models 3jag, resolution 3.65Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3jag is a 87 chain structure with sequence from [1] and Oryctolagus cuniculus. This structure supersedes the now removed PDB entry [2]. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: ADP, MG, SF4, ZN Related: 3jah, 3jai Resources: FirstGlance, OCA, RCSB, PDBsum Warning: this is a large structure, and loading might take a long time or not happen at all. Function [U3KPD5_RABIT] Binds to the 23S rRNA.[RuleBase:RU000576] [ERF1_HUMAN] Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. [G1SS70_RABIT] May play a role during erythropoiesis through regulation of transcription factor DDIT3.[HAMAP-Rule:MF_03122]

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