1ftn | pdb_00001ftn
From Proteopedia
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| 1ftn, resolution 2.1Å | |||||||||||||
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| Ligands: | MG and GDP | ||||||||||||
| Gene: | SYNTHETIC HUMAN RHOA GENE (Homo sapiens) | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX
Overview
RhoA, a ubiquitous intracellular GTPase, mediates cytoskeletal responses to extracellular signals. A 2.1 A resolution crystal structure of the human RhoA-GDP complex shows unique stereochemistry in the switch I region, which results in a novel mode of Mg2+ binding.
About this Structure
1FTN is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
Crystal structure of RhoA-GDP and its functional implications., Wei Y, Zhang Y, Derewenda U, Liu X, Minor W, Nakamoto RK, Somlyo AV, Somlyo AP, Derewenda ZS, Nat Struct Biol. 1997 Sep;4(9):699-703. PMID:9302995
Page seeded by OCA on Sun Mar 23 11:50:11 2008
