2ic5 | pdb_00002ic5

Crystal structure of human RAC3 grown in the presence of Gpp(NH)p.

spinqualitylabelsall models 2ic5, resolution 1.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2ic5 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: BTB, CL, GDP, GNP, MG Related: 2g0n Gene: RAC3 (HUMAN) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Function [RAC3_HUMAN] Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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