1rxa | pdb_00001rxa

CRYSTAL STRUCTURE OF R(CCCCGGGG) IN TWO DISTINCT LATTICES

spinqualitylabelsall models 1rxa, resolution 2.90Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1rxa is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Publication Abstract from PubMed The structure of the RNA octamer r(C4G4) has been determined in two different crystal forms. The conformations of the RNA duplex in the rhombohedral and hexagonal lattices display only minimal deviations, demonstrating that the RNA double helix is considerably less deformable than the DNA double helix. For the first time the crystal structures of an A-RNA and an A-DNA with identical sequence can now be compared. The large number of ordered water molecules observed in the minor groove of the RNA duplex suggests that an important contribution to its higher rigidity derives from the improved hydration due to the presence of the 2'-hydroxyl groups. Our finding that the conformation of the RNA double helix is virtually unaffected by different crystal packing modes provides evidence that proteins may not alter the conformation of RNA stem regions in a significant way. The crystal structure of r(CCCCGGGG) in two distinct lattices.,Portmann S, Usman N, Egli M Biochemistry. 1995 Jun 13;34(23):7569-75. PMID:7779802 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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