2kbm | pdb_00002kbm

Ca-S100A1 interacting with TRTK12

spinqualitylabelsall models 2kbm, 20 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2kbm is a 4 chain structure with sequence from Buffalo rat. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: CA Related: 2k2f, 1zfs Gene: Capza2 (Buffalo rat), S100a1 (Buffalo rat) Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Function [CAZA2_RAT] F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (By similarity). [S10A1_RAT] Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. See Also F-actin capping protein S100 protein

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