1yis | pdb_00001yis

Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase

spinqualitylabelsall models 1yis, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 1yis is a 1 chain structure with sequence from Caeel. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: SO4 NonStd Res: MSE Related: 1c3c, 1c3u, 1dof Activity: Adenylosuccinate lyase, with EC number 4.3.2.2 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, TOPSAN Function [PUR8_CAEEL] Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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