2f87 | pdb_00002f87

Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus

spinqualitylabelsall models 2f87, 13 NMR models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2f87 is a 1 chain structure. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Publication Abstract from PubMed The NMR structure of a 12-mer RNA derived from the helix 6 of SRP RNA from Pyrococcus furiosus, whose loop-closing base pair is U.G, was determined, and the structural and thermodynamic properties of the RNA were compared with those of a mutant RNA with the C:G closing base pair. Although the structures of the two RNAs are similar to each other and adopt the GNRR motif the conformational stabilities are significantly different to each other It was suggested that weaker stacking interaction of the GAAG loop with the U:G closing base pair in 12-mer RNA causes the lower conformational stability. Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus.,Okada K, Takahashi M, Sakamoto T, Kawai G, Nakamura K, Kanai A Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):383-95. PMID:16838833 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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