5hem | pdb_00005hem

Crystal structure of the N-terminus D161Y bromodomain mutant of human BRD2

spinqualitylabelsall models 5hem, resolution 1.65Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5hem is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: ACT, EDO, MG Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Function [BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.

Proteopedia Page Contributors and Editors (what is this?)

OCA