2w0v | pdb_00002w0v

CRYSTAL STRUCTURE OF GLMU FROM HAEMOPHILUS INFLUENZAE IN COMPLEX WITH QUINAZOLINE INHIBITOR 1

spinqualitylabelsall models 2w0v, resolution 1.99Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 2w0v is a 1 chain structure with sequence from "bacterium_influenzae"_lehmann_and_neumann_1896 "bacterium influenzae" lehmann and neumann 1896. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: LZR, PG4, PGE, SO4 Related: 2v0h, 2v0l, 2v0j, 2vd4, 2w0w, 2v0k, 2v0i Activity: Glucosamine-1-phosphate N-acetyltransferase, with EC number 2.3.1.157 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Function [GLMU_HAEIN] Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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