5fph | pdb_00005fph

The GTPase domains of the immunity-related Irga6 dimerize in a parallel head-to-head fashion

spinqualitylabelsall models 5fph, resolution 3.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 5fph is a 7 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Ligands: GNP, MG, TRS NonStd Res: MSE Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Function [IIGP1_MOUSE] GTPase with low activity. Has higher affinity for GDP than for GTP. Plays a role in resistance to intracellular pathogens. Required for disruption of the parasitophorous vacuole formed following T.gondii infection and subsequent killing of the parasite. Mediates resistance to C.trachomatis infection by targeting bacterial inclusions to autophagosomes for subsequent lysosomal destruction.

Proteopedia Page Contributors and Editors (what is this?)

OCA