5ajs | pdb_00005ajs
From Proteopedia
Crystal structure of a coiled-coil domain from human THAP11
| ||||||||||||
Structural highlights
Function[THA11_HUMAN] Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity). Contents | ||||||||||||||||
This page was last modified 03:52, 10 March 2016.