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You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
Introduction
Lysophosphatidic Acid Receptor 1 (commonly referred to as LPA1) is a G-protein coupled receptor(link) and one of 6 different LPA receptors (LPA1-LPA6) that bind the phospholipid derivative lysophosphatidic acid (LPA)-link?, a signaling molecule that acts as a potent mitogen upon binding to one of the six receptors. LPA is present in nearly all cells and tissues throughout the body, and deletion of the LPA1 receptor has shown to have physiological effects on every organ system. ----------- LPA1 is part of the larger EDG receptor family(link) which includes the more widely known sphingosine 1-phopshate receptors.
Structure
Key Ligand Interactions
GluLys
His
ArgGln
Function
Disease Relevance
Receptor Comparison
Sphingosine 1-Phosphate Receptor
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Endocannabinoid Receptor 1
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- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:https://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644