Haloperoxidase

spinqualitylabelsall models Bromoperoxidase complex with VO4 and I- (purple) ions, 1qi9 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Haloperoxidases catalyze the oxidation of halides by hydrogen peroxide while adding a halide to hydrocarbons. They are classified as chloroperoxldase (CPO), bromoperoxidase (BPO) and iodoperoxidase (IPO) according to the halide which they oxidize. CPO is heme-containing, vanadium-containing or metal-free. BPO from marine algae is vanadium-containing. Structural highlights The vanadate ion shows a trigonal bipyramidal coordination. The iodine atoms are coordinated to tyrosine residue.

3D structures of haloperoxidase

Updated on 28-March-2016

{"openlevels":0}

• Vanadium-containing chloroperoxidase
  • 1vnc, 1vni, 1idq, 1idu – CiCPO – Curvularia inaequalis
    
  • 1vne, 1vnf, 1vng, 1vnh – CiCPO (mutant)
    
  • 1vns – CiCPO no vanadium
• Heme-containing chloroperoxidase
  • 1cpo, 2cpo – LfCPO – Leptoxyphium fumago
    
  • 2civ – LfCPO + Br
    
  • 2ciw – LfCPO + I
    
  • 2cix – LfCPO + cyclopentane-dione + Br
    
  • 2ciy – LfCPO + CN + DMSO + Br
    
  • 2ciz – LfCPO + acetate + Br
    
  • 2cj0 – LfCPO + nitrate
    
  • 2cj1, 2cj2 – LfCPO + formate
    
  • 2j5m – LfCPO + H2O2
• Metal-free chloroperoxidase
  • 1a7u - SaCPO T – Streptomyces aureofaciens
    
  • 1a8s – PfCPO F + propanoic acid – Pseudomonas fluorescens
    
  • 1a8u – PfCPO T + benzoic acid
    
  • 1a88 - CPO L – Streptomyces lividans
• Metal-free bromoperoxidase
  • 1a8q – SaBPO A1
    
  • 1bro - SaBPO A2
    
  • 1brt – SaBPO A2 (mutant)
    
  • 3fob – BPO – Bacillus anthracis
• Vanadium-containing bromoperoxidase
  • 1qi9 – BPO + I – Ascophyllum nodosum
    
  • 1up8, 1qhb – BPO no vanadium – Corallina pilulifera
• Vanadium-containing iodoperoxidase
  • 4cit, 4usz – IPO + VO4 – Zobellia galactanivorans
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky