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Human metabotropic glutamate receptor 5 transmembrane domain

<StructureSection load='4oo9' size='350' frame='true' side='right' caption='Human metabotropic glutamate receptor 5 transmembrane domain' <'scene='(Ionic_lock)'> The Human metabotropic glutamate receptor 5 transmembrane domain is a

Structure

Cross section view of mavoglurant in the binding pocket

Extracellular Domain

This is the Extracellular Loops ECL 1, 2, and 3 highlighted in purple

Disulfide Bond The Disulfide bond is attached to Helix 3 and the Amino Acid chain connected to Helix 5 and the N terminus

Binding Pocket

Figure Legend

Mavoglurant Mavoglurant is in the 7 Transmembrane Domain Pocket. Also, the lysozyme is attached to the intercellular region of the 7 Transmembrane Domain.

Disease