Sandbox WWC6

Function

Alpha-hemolysin [1] is a toxin secreted by Staphylococcus aureus as a pore-forming heptamer that binds to eukaryotic cell membranes. This protein belongs to a family of bacterial exotoxins[2]. The primary function of alpha-hemolysin is cytolytic, and is achieved by the release of cytosolic K⁺ ions from the through the hydrophilic, transmembrane portion of the beta-barrel pore[3].

spinqualitylabelsall models 1pgb Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D

N to C Sequence

Amino Terminus

Carboxy Terminus

Let us color the two main forms of regular Secondary Structure in this protein. Alpha Helices appears in red,  Beta Strands  in yellow.

How many alpha helices are in this structure?

	None.
	One.
	Four.

Tacrine within 1acj